Important parameters to be considered when comparing gene therapy vectors include: size limitations for transgene insertion, ease production of virus at high titers, trans- duction efficiency, ability to infect dividing andor quiescent cells, stability of transgene expression, potential to integrate into the host chromosomes, cell-type specificity, vector-associated toxicity and immunogenicity (tables 2.
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8 PRACTICAL STUDIES OF MASS TRANSFER The albdrta applications of mass transfer are in the fields of distillation, gas absorption and the other separation processes involving mass transfer which are discussed in Volume 2, In particular, mass transfer coefficients and heights of transfer units in distillation, and in gas absorption are discussed in Volume 2.
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294 INDEX Antagonism (continued) Gaddum equation for, 122, 125 nonsurmountable, 99 operational classifications of, 127 operational definition of, 99 orthosteric allosteric antagonism differentiated from, 141, 208 definition of, 99 insurmountable, 125 operational model with variable slope, 222 pA2 and pKB for, 125 resultant analysis, 119120, 125126, 264266 phases of, 209210 short-form measures of, 209218 surmountable definition of, 99 description of, 99, 102, 207208 inverse agonists, 108111 partial agonists, 111113 Schild analysis.
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